Gene

aspn

ID
ZDB-GENE-041105-7
Name
asporin (LRR class 1)
Symbol
aspn Nomenclature History
Previous Names
  • aspnl
  • bgl3
  • wu:fk08c11
  • zgc:109936
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and collagen binding activity. Predicted to localize to extracellular space. Is expressed in axial vasculature; chondrocranium; and pharyngeal arch. Human ortholog(s) of this gene implicated in ankylosing spondylitis; degenerative disc disease; and osteoarthritis. Orthologous to human ASPN (asporin).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aspn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Lumbar disc degeneration} 603932
{Osteoarthritis susceptibility 3} 607850
Associated With aspn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Family IPR016352 Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
Family IPR028548 Asporin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Asporin Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
UniProtKB:Q1LXA7 370
UniProtKB:Q1LXA6 161
UniProtKB:Q6DBT8 190
UniProtKB:A8BBD1 370
UniProtKB:Q9DE02 120
UniProtKB:Q504E0 370
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations