Gene
aspn
- ID
- ZDB-GENE-041105-7
- Name
- asporin (LRR class 1)
- Symbol
- aspn Nomenclature History
- Previous Names
-
- aspnl
- bgl3
- wu:fk08c11
- zgc:109936
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and collagen binding activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in ankylosing spondylitis; degenerative disc disease; and osteoarthritis. Is expressed in axial vasculature; chondrocranium; and pharyngeal arch. Orthologous to human ASPN (asporin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109936 (8 images)
- eu237 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000372 | Leucine-rich repeat N-terminal domain |
| Family | IPR016352 | Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
Domain Details Per Protein
| Protein | Length | Leucine-rich repeat | Leucine-rich repeat domain superfamily | Leucine-rich repeat N-terminal domain | Leucine-rich repeat, typical subtype | Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan |
|---|---|---|---|---|---|---|
|
UniProtKB:Q1LXA7
|
370 | |||||
|
UniProtKB:Q6DBT8
|
190 |
Interactions and Pathways
No data available
Plasmids
No data available