Gene

aspn

ID
ZDB-GENE-041105-7
Name
asporin (LRR class 1)
Symbol
aspn Nomenclature History
Previous Names
  • aspnl
  • bgl3
  • wu:fk08c11
  • zgc:109936
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity and collagen binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in axial vasculature; chondrocranium; and pharyngeal arch. Human ortholog(s) of this gene implicated in ankylosing spondylitis; degenerative disc disease; and osteoarthritis. Orthologous to human ASPN (asporin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aspn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Lumbar disc degeneration} 603932
{Osteoarthritis susceptibility 3} 607850
Associated With aspn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Family IPR016352 Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
Family IPR028547 Biglycan
Family IPR028548 Asporin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Asporin Biglycan Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
UniProtKB:Q1LXA7 370
UniProtKB:A8BBD1 370
UniProtKB:Q6DBT8 190
UniProtKB:Q1LXA6 161
UniProtKB:Q9DE02 120
UniProtKB:Q504E0 370
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations