ZFIN ID: ZDB-GENE-041027-2
Gene Name: myosin VAa
Gene Symbol: myo5aa    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: myo5a, si:dkey-266j9.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity; actin-dependent ATPase activity; and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to localize to actin cytoskeleton; cytoplasm; and vesicle. Is expressed in central nervous system; dorsolateral placode; intestine; neural tube; and neuron neural crest derived. Human ortholog(s) of this gene implicated in Griscelli syndrome type 1. Orthologous to human MYO5A (myosin VA).
Genome Resources: Alliance (1),  Gene:562188 (1),  Ensembl(GRCz11):ENSDARG00000061635 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH myo5aa HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Griscelli syndrome type 1 Alliance Griscelli syndrome, type 1 214450
DISEASE ASSOCIATED WITH myo5aa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process actin filament organization (more)
Cellular Component myosin complex (more)
Molecular Function actin binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA myo5aa-202 (1)    Ensembl 5535
myo5aa-203 (1)    Ensembl 844
myo5aa-204 (1)    Ensembl 5735
ncRNA myo5aa-005 (1) 815
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myo5aa No data available
MARKER RELATIONSHIPS
myo5aa Contained in: [BAC] CH211-143E19 (1), DKEY-266J9 (1) (order this)
myo5aa Encodes: [cDNA] MGC:195213 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_005173675 (1) 5901 nt
Genomic RefSeq:NW_018395043 (1) Blast at MegaBLAST
Polypeptide UniProtKB:B3DJR2 (1) 1891 aa
Sequence Information (all 65)
ORTHOLOGY for myo5aa ( Chr: 18 )
CITATIONS (32)