ZFIN ID: ZDB-GENE-041014-72
Gene Name: INO80 complex ATPase subunit
Gene Symbol: ino80    Nomenclature History

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Previous Name: si:ch211-244p18.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to contribute to 3'-5' DNA helicase activity. Predicted to be involved in DNA repair; chromatin remodeling; and regulation of transcription from RNA polymerase II promoter in response to stress. Predicted to localize to the Ino80 complex. Orthologous to human INO80 (INO80 complex ATPase subunit).
Genome Resources: Alliance (1),  Gene:566768 (1),  Ensembl(GRCz11):ENSDARG00000070432 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa765 Point Mutation Unknown Splice Site ENU
sa15927 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23725 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43459 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ino80 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ino80 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ino80 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chromatin remodeling (more)
    Cellular Component Ino80 complex (more)
    Molecular Function ATPase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000330 SNF2-related, N-terminal domain
    Domain IPR001650 Helicase, C-terminal
    Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
    Domain IPR020838 DBINO domain
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    Family IPR031047 DNA helicase Ino80
    Homologous_superfamily IPR038718 SNF2-like, N-terminal domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ino80-201 (1)    Ensembl 5814
    ncRNA ino80-002 (1)    Ensembl 709
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ino80 No data available
    MARKER RELATIONSHIPS
    ino80 Contained in: [BAC] CH211-244P18 (1), DKEY-14A13 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045119 (1) 5814 bp
    Genomic GenBank:AL929049 (1) 223182 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8PY80 (1) 1591 aa
    Sequence Information (all 22)
    ORTHOLOGY for ino80 ( Chr: 20 )
    CITATIONS (17)