Gene

rfx6

ID
ZDB-GENE-041014-299
Name
regulatory factor X, 6
Symbol
rfx6 Nomenclature History
Previous Names
  • si:dkeyp-93d12.2
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in endocrine pancreas development. Predicted to localize to nucleus. Is expressed in intestine; pancreas; pancreas primordium; and pancreatic bud. Orthologous to human RFX6 (regulatory factor X6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Soyer et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rfx6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mitchell-Riley syndrome 615710
Associated With rfx6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003150 DNA-binding RFX-type winged-helix domain
Family IPR039779 RFX-like DNA-binding protein
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length DNA-binding RFX-type winged-helix domain RFX-like DNA-binding protein Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q5RJA1 848
UniProtKB:F1R701 907
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations