ZFIN ID: ZDB-GENE-041014-121
Gene Name: p21 protein (Cdc42/Rac)-activated kinase 6b
Gene Symbol: pak6b    Nomenclature History

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Previous Names: pak6 (1), si:ch211-158b22.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; signal transduction by protein phosphorylation; and stress-activated protein kinase signaling cascade. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough).
Genome Resources: Alliance (1),  Gene:567874 (1),  Ensembl(GRCz11):ENSDARG00000052405 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a312 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-pak6b 1
CRISPR2-pak6b 1
CRISPR3-pak6b 1
CRISPR4-pak6b 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pak6b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH pak6b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pak6b-202 (1)    Ensembl 2203
pak6b-203 (1)    Ensembl 451
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pak6b No data available
MARKER RELATIONSHIPS
pak6b Contained in: [BAC] CH211-158B22 (1)
[Fosmid] CH1073-184E3 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001162487 (1) 1824 nt
Genomic GenBank:AL772143 (1) 73696 nt
Select Tool
Polypeptide UniProtKB:A5PEY8 (1) 607 aa
Sequence Information (all 11)
ORTHOLOGY for pak6b ( Chr: 20 )
CITATIONS (17)