ZFIN ID: ZDB-GENE-041010-92
Gene Name: serine/threonine kinase 25a
Gene Symbol: stk25a    Nomenclature History

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Previous Names: stk25b (1), zgc:92836

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Involved in axis elongation and heart development. Predicted to localize to the cytoplasm. Is expressed in cranial ganglion and pharyngeal arch. Orthologous to human STK25 (serine/threonine kinase 25).
Genome Resources: Alliance (1),  Gene:449653 (1),  Ensembl(GRCz11):ENSDARG00000002210 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [MGC:92836]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa18659 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-stk25a N/A 1
    MO2-stk25a N/A 1
    DISEASE ASSOCIATED WITH stk25a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH stk25a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart development (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Binding_site IPR017441 Protein kinase, ATP binding site
    Domain IPR000719 Protein kinase domain
    Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA stk25a-203 (1)    Ensembl 1922
    ncRNA stk25a-003 (1)    Ensembl 886
    stk25a-004 (1)    Ensembl 665
    stk25a-005 (1)    Ensembl 509
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM stk25a No data available
    MARKER RELATIONSHIPS
    stk25a Contained in: [BAC] DKEY-107H14 (1) (order this)
    stk25a Encodes: [cDNA] MGC:92836 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001005925 (1) 1776 nt
    Genomic GenBank:CU467043 (1) 135926 nt
    Select Tool
    Polypeptide UniProtKB:F8W562 (1) 421 aa
    Sequence Information (all 14)
    ORTHOLOGY for stk25a ( Chr: 6 )
    CITATIONS (20)