Gene

galk1

ID
ZDB-GENE-041010-79
Name
galactokinase 1
Symbol
galk1 Nomenclature History
Previous Names
  • zgc:101541
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have galactokinase activity. Predicted to be involved in galactose metabolic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in cataract and galactokinase deficiency. Orthologous to human GALK1 (galactokinase 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With galk1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
galactokinase deficiency Alliance Galactokinase deficiency with cataracts 230200
Associated With galk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006203 GHMP kinase, ATP-binding, conserved site
Conserved_site IPR019741 Galactokinase, conserved site
Domain IPR006204 GHMP kinase N-terminal domain
Domain IPR013750 GHMP kinase, C-terminal domain
Domain IPR019539 Galactokinase, N-terminal domain
Family IPR000705 Galactokinase
Family IPR006206 Mevalonate/galactokinase
Homologous_superfamily IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR036554 GHMP kinase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Galactokinase Galactokinase, conserved site Galactokinase, N-terminal domain GHMP kinase, ATP-binding, conserved site GHMP kinase, C-terminal domain GHMP kinase, C-terminal domain superfamily GHMP kinase N-terminal domain Mevalonate/galactokinase Ribosomal protein S5 domain 2-type fold Ribosomal protein S5 domain 2-type fold, subgroup
UniProtKB:F1R3T4 393
UniProtKB:Q5XJU9 393
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations