ZFIN ID: ZDB-GENE-041010-70
Gene Name: abraxas 1, BRCA1 A complex subunit
Gene Symbol: abraxas1    Nomenclature History

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Previous Names: abraxas2a, ccdc98 (1), fam175a, zgc:103522

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including mitotic spindle assembly; protein K63-linked deubiquitination; and signal transduction involved in G2 DNA damage checkpoint. Predicted to localize to BRCA1-A complex. Orthologous to human ABRAXAS1 (abraxas 1, BRCA1 A complex subunit).
Genome Resources: Alliance (1),  Gene:449820 (1),  Ensembl(GRCz11):ENSDARG00000043339 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7157614]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11677 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abraxas1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH abraxas1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process double-strand break repair (more)
    Cellular Component BRCA1-A complex (more)
    Molecular Function polyubiquitin modification-dependent protein binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abraxas1-201 (1)    Ensembl 1671
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abraxas1 No data available
    MARKER RELATIONSHIPS
    abraxas1 Contained in: [BAC] CH211-85E10 (1)
    abraxas1 Encodes: [EST] IMAGE:7157614 (1)
    [cDNA] MGC:103522 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001005993 (1) 1439 nt
    Genomic GenBank:BX649525 (1) 180584 nt
    Select Tool
    Polypeptide UniProtKB:Q1LVP6 (1) 391 aa
    Sequence Information (all 16)
    ORTHOLOGY for abraxas1 ( Chr: 21 )
    CITATIONS (20)