Gene

wacb

ID
ZDB-GENE-041010-46
Name
WW domain containing adaptor with coiled-coil b
Symbol
wacb Nomenclature History
Previous Names
  • zgc:101828
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in histone monoubiquitination; positive regulation of TORC1 signaling; and regulation of autophagy. Predicted to act upstream of or within chromatin organization. Predicted to be active in nucleus. Orthologous to human WAC (WW domain containing adaptor with coiled-coil).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wacb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Desanto-Shinawi syndrome 616708
Associated With wacb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001202 WW domain
Family IPR038867 WW domain-containing adapter protein with coiled-coil
Homologous_superfamily IPR036020 WW domain superfamily
Domain Details Per Protein
Protein Length WW domain WW domain-containing adapter protein with coiled-coil WW domain superfamily
UniProtKB:Q5XJK7 269
UniProtKB:A0A0R4IQS4 155
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations