Gene
wacb
- ID
- ZDB-GENE-041010-46
- Name
- WW domain containing adaptor with coiled-coil b
- Symbol
- wacb Nomenclature History
- Previous Names
-
- zgc:101828
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II complex binding activity and chromatin binding activity. Predicted to be involved in positive regulation of TORC1 signaling and regulation of autophagy. Predicted to act upstream of or within chromatin organization. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in DeSanto-Shinawi syndrome. Orthologous to human WAC (WW domain containing adaptor with coiled-coil).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101828 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| DeSanto-Shinawi syndrome | Alliance | Desanto-Shinawi syndrome | 616708 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | WW domain | WW domain-containing adapter protein with coiled-coil | WW domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q5XJK7 | InterPro | 269 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available