Gene

gpd1l

ID
ZDB-GENE-041010-220
Name
glycerol-3-phosphate dehydrogenase 1 like
Symbol
gpd1l Nomenclature History
Previous Names
  • wu:fi13g03
  • wu:fi45b08
  • zgc:92580
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have NAD binding activity; glycerol-3-phosphate dehydrogenase [NAD+] activity; and protein homodimerization activity. Predicted to be involved in carbohydrate metabolic process and glycerol-3-phosphate catabolic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Orthologous to human GPD1L (glycerol-3-phosphate dehydrogenase 1 like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gpd1l Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Brugada syndrome 2 Alliance Brugada syndrome 2 611777
Associated With gpd1l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
Domain IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
Family IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent
Family IPR017751 Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic
Homologous_superfamily IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Homologous_superfamily IPR013328 6-phosphogluconate dehydrogenase, domain 2
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 6-phosphogluconate dehydrogenase, domain 2 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Glycerol-3-phosphate dehydrogenase, NAD-dependent Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal NAD(P)-binding domain superfamily
UniProtKB:Q5XIZ6 351
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations