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ZIRC
ZFIN ID: ZDB-GENE-041010-219
Gene Name: acyl-CoA oxidase 1, palmitoyl
Gene Symbol: acox1    Nomenclature History

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Previous Names: wu:fb59h12, zgc:114033, zgc:92584

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have fatty acid binding activity; flavin adenine dinucleotide binding activity; and palmitoyl-CoA oxidase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis; and very long-chain fatty acid metabolic process. Predicted to localize to the peroxisome. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Is expressed in several structures, including female organism; heart; immature eye; liver; and pleuroperitoneal region. Orthologous to human ACOX1 (acyl-CoA oxidase 1).
Genome Resources: Alliance (1),  Gene:449662 (1),  Ensembl(GRCz11):ENSDARG00000014727 (2)
GENE EXPRESSION
All Expression Data: 12 figures from 9 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92584]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5364 Point Mutation Unknown Premature Stop ENU
sa13596 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16860 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acox1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    peroxisomal acyl-CoA oxidase deficiency Alliance Peroxisomal acyl-CoA oxidase deficiency 264470
    DISEASE ASSOCIATED WITH acox1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid beta-oxidation (more)
    Cellular Component peroxisome (more)
    Molecular Function acyl-CoA oxidase activity (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acox1-201 (1)    Ensembl 2662
    acox1-202 (1)    Ensembl 2578
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acox1 No data available
    MARKER RELATIONSHIPS
    acox1 Contained in: [BAC] CH211-89I1 (1) (order this)
    acox1 Encodes: [EST] fb59h12 (1)
    [cDNA] MGC:92584 (1) (order this), MGC:114033 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005933 (1) 2615 bp
    Genomic GenBank:CR391945 (1) 103052 bp
    Select Tool
    Polypeptide UniProtKB:F1R071 (1) 660 aa
    Sequence Clusters UniGene:36780 (1)
    Sequence Information (all 19)
    ORTHOLOGY for acox1 ( Chr: 6 )
    CITATIONS (45)