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ZIRC
ZFIN ID: ZDB-GENE-041010-217
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Gene Name: RAS related
Gene Symbol: rras    Nomenclature History

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Previous Names: fb23a02, wu:fb23a02, wu:fj98h09, zgc:92588 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Involved in Notch signaling pathway and maintenance of epithelial cell apical/basal polarity. Predicted to localize to the plasma membrane. Is expressed in hindbrain and somite. Orthologous to human RRAS (RAS related).
Genome Resources: Alliance (1),  Gene:449660 (1),  Ensembl(GRCz11):ENSDARG00000006553 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92588]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024117Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • muu1 Indel Exon 3 Frameshift, Premature Stop CRISPR
    muu2 Small Deletion Exon 3 Frameshift, Premature Stop CRISPR
    sa7267 Point Mutation Unknown Splice Site ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rras 1
    CRISPR2-rras 1
    MO1-rras N/A 2
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH rras HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rras VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process maintenance of epithelial cell apical/basal polarity (more)
    Cellular Component membrane (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001806 (1)
  • InterPro:IPR005225 (1)
  • InterPro:IPR020849 (1)
  • InterPro:IPR027417 (1)
  • PROSITE:PS51421 (1)
  • Pfam:PF00071 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rras-201 (1)    Ensembl 2510
    Select Tool
    rras-203 (1)    Ensembl 571
    Select Tool
    ncRNA rras-003 (1)    Ensembl 716
    Select Tool
    rras-004 (1)    Ensembl 855
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rras No data available
    MARKER RELATIONSHIPS
    rras Contained in: [BAC] CH211-195B15 (1) (order this)
    rras Encodes: [EST] fb23a02, fj98h09 (1)
    [cDNA] MGC:92588 (1) (order this), MGC:113825 (1), MGC:191120 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001005931 (1) 2345 bp
    Select Tool
    Genomic GenBank:CR936975 (1) 121737 bp
    Select Tool
    Polypeptide UniProtKB:Q4V9D8 (1) 196 aa
    Select Tool
    Sequence Clusters UniGene:76729 (1)
    Sequence Information (all 23)
    ORTHOLOGY for rras ( Chr: 3 )
    CITATIONS (30)