ZFIN ID: ZDB-GENE-041010-193
Gene Name: mitoguardin 1
Gene Symbol: miga1    Nomenclature History

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Previous Names: fam73a (1), zgc:101625 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in mitochondrial fusion. Predicted to localize to integral component of plasma membrane. Orthologous to human MIGA1 (mitoguardin 1).
Genome Resources: Alliance (1),  Gene:450070 (1),  Ensembl(GRCz11):ENSDARG00000020596 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101625]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7159735]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa38312 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH miga1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH miga1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitochondrial fusion (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA miga1-201 (1)    Ensembl 2471
    ncRNA fam73a-002 (1)    Ensembl 485
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM miga1 No data available
    MARKER RELATIONSHIPS
    miga1 Contained in: [BAC] CH211-71M22 (1), CH211-284G18 (1)
    miga1 Encodes: [EST] IMAGE:7159735 (1)
    [cDNA] MGC:101625 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001006090 (1) 2064 nt
    Genomic GenBank:BX649634 (1) 154030 nt
    Select Tool
    Polypeptide UniProtKB:A5PMR5 (1) 595 aa
    Sequence Information (all 14)
    ORTHOLOGY for miga1 ( Chr: 2 )
    CITATIONS (25)