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ZIRC
ZFIN ID: ZDB-GENE-041010-191
Gene Name: N-acylsphingosine amidohydrolase (acid ceramidase) 1a
Gene Symbol: asah1a
Sequence Ontology ID : SO:0000704

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Previous Names: asah1, zgc:101637

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have N-acylsphingosine amidohydrolase activity. Predicted to be involved in lipid metabolic process. Predicted to localize to the lysosome. Human ortholog(s) of this gene implicated in  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6903483]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1537 Point Mutation Unknown Premature Stop ENU
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH asah1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Farber lipogranulomatosis Farber lipogranulomatosis 228000
Spinal muscular atrophy with progressive myoclonic epilepsy 159950
DISEASE ASSOCIATED WITH asah1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process lipid metabolic process (more)
Cellular Component lysosome (more)
Molecular Function hydrolase activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR016699 (1)
  • InterPro:IPR029130 (1)
  • InterPro:IPR029132 (1)
  • Pfam:PF02275 (1)
  • Pfam:PF15508 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA asah1a-002 (1) 527
    mRNA asah1a-201 (1) 2007
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM asah1a No data available
    MARKER RELATIONSHIPS
    asah1aContained in: [BAC] DKEYP-46F3 (1)
    asah1aEncodes: [EST] IMAGE:6903483 (1) (order this)
    [cDNA] MGC:101637 (1) (order this), MGC:173782 (1) (order this), MGC:192875 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001006088 (1) 1578bp
    Genomic GenBank:BX323012 (1) 175238bp
    Select Tool
    Polypeptide UniProtKB:A8E524 (1) 390aa
    Sequence Clusters UniGene:36953 (1)
    Sequence Information (all 23)
    ORTHOLOGY for asah1a (Chr: 14)
    CITATIONS (22)