ZFIN ID: ZDB-GENE-041010-179
Gene Name: TBC1 domain family, member 16
Gene Symbol: tbc1d16    Nomenclature History

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Previous Names: fi28h02, wu:fi28h02, zgc:101681

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have GTPase activator activity and Rab GTPase binding activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Predicted to localize to the early endosome. Orthologous to human TBC1D16 (TBC1 domain family member 16).
Genome Resources: Alliance (1),  Gene:450056 (1),  Ensembl(GRCz11):ENSDARG00000036994 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101681]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023944Tg Transgenic Insertion Unknown Unknown DNA
sa505 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tbc1d16 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tbc1d16 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process activation of GTPase activity (more)
    Cellular Component early endosome (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000195 Rab-GTPase-TBC domain
    Homologous_superfamily IPR035969 Rab-GTPase-TBC domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tbc1d16-201 (1)    Ensembl 1265
    tbc1d16-202 (1)    Ensembl 2660
    ncRNA tbc1d16-002 (1) 594
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tbc1d16 No data available
    MARKER RELATIONSHIPS
    tbc1d16 Contained in: [BAC] CH73-46L13 (1), CH73-54C11, CH211-139G16 (1), CH211-246E12 (1)
    tbc1d16 Encodes: [EST] fi28h02
    [cDNA] MGC:101681 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001006076 (1)
    Genomic GenBank:CT573440 (1) 159035 bp
    Select Tool
    Polypeptide UniProtKB:E7FE32 (1) 717 aa
    Sequence Information (all 15)
    ORTHOLOGY for tbc1d16 ( Chr: 3 )
    CITATIONS (21)