ZFIN ID: ZDB-GENE-041010-172
Gene Name: dehydrogenase/reductase (SDR family) member 3b
Gene Symbol: dhrs3b    Nomenclature History

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Previous Names: ik:tdsubc_1f3, tdsubc_1f3, xx:tdsubc_1f3, zgc:101705

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have retinol dehydrogenase activity. Predicted to be involved in regulation of retinoic acid receptor signaling pathway and retinoid metabolic process. Predicted to localize to lipid droplet. Is expressed in several structures, including axis; margin; myotome; nervous system; and ventral mesoderm. Orthologous to human DHRS3 (dehydrogenase/reductase 3).
Genome Resources: Alliance (1),  Gene:450050 (1),  Ensembl(GRCz11):ENSDARG00000044803 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010509Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027262Tg Transgenic Insertion Unknown Unknown DNA
    sa14805 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dhrs3b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dhrs3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process retinol metabolic process (more)
    Cellular Component lipid droplet (more)
    Molecular Function retinol dehydrogenase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dhrs3b-201 (1)    Ensembl 1652
    ncRNA dhrs3b-002 (1)    Ensembl 863
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dhrs3b No data available
    MARKER RELATIONSHIPS
    dhrs3b Contained in: [BAC] CH211-226M7 (1)
    dhrs3b Encodes: [EST] IMAGE:7155647 (1), tdsubc_1f3
    [cDNA] MGC:101705 (1), MGC:191245 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001006070 (1) 1671 nt
    Genomic GenBank:BX470199 (1) 197146 nt
    Select Tool
    Polypeptide UniProtKB:F1QID5 (1) 302 aa
    Sequence Information (all 15)
    ORTHOLOGY for dhrs3b ( Chr: 11 )
    CITATIONS (24)