Gene

chga

ID
ZDB-GENE-041010-161
Name
chromogranin A
Symbol
chga Nomenclature History
Previous Names
  • fj05f09
  • si:dkey-177p2.2
  • wu:fj05f09
  • zgc:101749
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation; defense response to bacterium; and negative regulation of secretion by cell. Predicted to be located in extracellular region and secretory granule. Predicted to be active in chromaffin granule and extracellular space. Is expressed in nervous system; otic vesicle; trigeminal placode; and trunk neural crest. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypertension; and prostate cancer. Orthologous to human CHGA (chromogranin A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chga Human Ortholog
No data available
Associated With chga Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018054 Chromogranin, conserved site
Family IPR001819 Chromogranin A/B
Family IPR001990 Chromogranin A/B/C
Domain Details Per Protein
Protein Length Chromogranin A/B Chromogranin A/B/C Chromogranin, conserved site
UniProtKB:A0A0B5JWD1 371
UniProtKB:Q5XJN4 362
UniProtKB:Q5RIJ8 369
UniProtKB:Q5RIJ7 246
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations