ZFIN ID: ZDB-GENE-041010-156
Gene Name: zgc:101765
Gene Symbol: zgc:101765    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 2. Orthologous to human AKR1D1 (aldo-keto reductase family 1 member D1).
Genome Resources: Alliance (1),  Gene:450036 (1),  Ensembl(GRCz11):ENSDARG00000054934 (1)

Nomenclature Note: This gene is characterized by full length cDNAs isolated as part of the Zebrafish Gene Collection (ZGC). When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix `zgc:' indicates that this gene is represented by cDNAs generated by the ZGC project.

GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101765]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa34064 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zgc:101765 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH zgc:101765 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cellular_component (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR018170 Aldo/keto reductase, conserved site
    Family IPR020471 Aldo/keto reductase
    Domain IPR023210 NADP-dependent oxidoreductase domain
    Homologous_superfamily IPR036812 NADP-dependent oxidoreductase domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zgc:101765-201 (1)    Ensembl 1604
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zgc:101765 No data available
    MARKER RELATIONSHIPS
    zgc:101765 Contained in: [BAC] DKEY-23I12 (1) (order this)
    zgc:101765 Encodes: [cDNA] MGC:101765 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001006056 (1) 1573 bp
    Genomic GenBank:AL954715 (1) 195884 bp
    Select Tool
    Polypeptide UniProtKB:Q5XJM7 (1) 288 aa
    Sequence Information (all 9)
    ORTHOLOGY for zgc:101765 ( Chr: 7 )
    CITATIONS (14)