Gene
cldn5b
- ID
- ZDB-GENE-041010-140
- Name
- claudin 5b
- Symbol
- cldn5b Nomenclature History
- Previous Names
-
- zgc:103419
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in anchoring junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in several structures, including brain; cardiovascular system; head; pleuroperitoneal region; and ventral mesoderm. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 24 figures from 17 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103419 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Bonkhofer et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Claudin | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|---|
| UniProtKB:F1R5J2 | InterPro | 220 | |||
| UniProtKB:A0A2R8Q6I0 | InterPro | 217 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cldn5b-201
(1)
|
Ensembl | 1,647 nt | ||
| mRNA |
cldn5b-202
(1)
|
Ensembl | 661 nt |
Interactions and Pathways
No data available
Plasmids