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Gene

ctsz

ID
ZDB-GENE-041010-139
Name
cathepsin Z
Symbol
ctsz Nomenclature History
Previous Names
  • wu:fj81f10
  • zgc:103420
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable cysteine-type endopeptidase activity. Acts upstream of or within angiogenesis. Predicted to be active in extracellular space and lysosome. Is expressed in blood; cardiovascular system; intestinal bulb; macrophage; and yolk syncytial layer. Orthologous to human CTSZ (cathepsin Z).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ctsz Human Ortholog
No data available
Associated With ctsz Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR025661 Cysteine peptidase, asparagine active site
Domain IPR000668 Peptidase C1A, papain C-terminal
Family IPR033157 Cathepsin Z
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Cathepsin Z Cysteine peptidase, asparagine active site Papain-like cysteine peptidase superfamily Peptidase C1A, papain C-terminal
UniProtKB:F8W3E6 138
UniProtKB:Q5XJD4 301
UniProtKB:F1RDQ9 301
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations