ZFIN ID: ZDB-GENE-041010-136
Gene Name: heat shock protein family, member 7 (cardiovascular)
Gene Symbol: hspb7    Nomenclature History

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Previous Name: zgc:103426

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Involved in several processes, including Kupffer's vesicle development; cardioblast migration to the midline involved in heart rudiment formation; and determination of left/right symmetry. Used to study heart disease. Is expressed in several structures, including Kupffer's vesicle; adaxial cell; cardiovascular system; musculature system; and pericardial region. Orthologous to human HSPB7 (heat shock protein family B (small) member 7).
Genome Resources: Alliance (1),  Gene:450019 (1),  Ensembl(GRCz11):ENSDARG00000104441 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24327 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30739 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • wcm3 Indel Unknown Frameshift TALEN
    wcm4 Indel Unknown Frameshift, Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hspb7 N/A 2
    MO2-hspb7 N/A 1
    MO3-hspb7 N/A 1
    MO4-hspb7 N/A 2
    MO5-hspb7 N/A 1
    TALEN1-hspb7 2
    DISEASE ASSOCIATED WITH hspb7 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of heart left/right asymmetry (more)
    Molecular Function molecular_function (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002068 Alpha crystallin/Hsp20 domain
    Domain IPR037885 Heat shock protein beta-7, ACD domain
    Family IPR001436 Alpha crystallin/Heat shock protein
    Homologous_superfamily IPR008978 HSP20-like chaperone
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hspb7 No data available
    MARKER RELATIONSHIPS
    hspb7 Encodes: [cDNA] MGC:103426 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001006040 (1)
    Genomic GenBank:CABZ01009162 (1) 13995 nt
    Polypeptide UniProtKB:A0A0R4IC54 (1) 161 aa
    Sequence Information (all 10)
    ORTHOLOGY for hspb7 ( Chr: 23 )
    CITATIONS (23)