Gene

pcyt2

ID
ZDB-GENE-041010-132
Name
phosphate cytidylyltransferase 2, ethanolamine
Symbol
pcyt2 Nomenclature History
Previous Names
  • im:7158585
  • wu:fb39h11
  • zgc:103434 (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have catalytic activity. Predicted to be involved in biosynthetic process. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia. Is expressed in central nervous system; cranial ganglion; epiphysis; and ventral mesoderm. Orthologous to human PCYT2 (phosphate cytidylyltransferase 2, ethanolamine).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Vaz et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pcyt2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 82 Alliance Spastic paraplegia 82, autosomal recessive 618770
Associated With pcyt2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004821 Cytidyltransferase-like domain
Domain IPR041723 CTP:phosphocholine cytidylyltransferase domain
Family IPR044608 Ethanolamine-phosphate cytidylyltransferase
Homologous_superfamily IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Domain Details Per Protein
Protein Length CTP:phosphocholine cytidylyltransferase domain Cytidyltransferase-like domain Ethanolamine-phosphate cytidylyltransferase Rossmann-like alpha/beta/alpha sandwich fold
UniProtKB:Q5XJC6 397
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations