Gene

csrp3

ID
ZDB-GENE-041010-119
Name
cysteine and glycine-rich protein 3 (cardiac LIM protein)
Symbol
csrp3 Nomenclature History
Previous Names
  • csrp3b (1)
  • Muscle LIM protein (1)
  • zgc:103468
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have actinin binding activity. Involved in heart contraction and sarcomere organization. Predicted to localize to Z disc and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Is expressed in musculature system; pericardial region; and trunk. Orthologous to human CSRP3 (cysteine and glycine rich protein 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With csrp3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dilated cardiomyopathy 1M Alliance ?Cardiomyopathy, dilated, 1M 607482
hypertrophic cardiomyopathy 12 Alliance Cardiomyopathy, hypertrophic, 12 612124
Associated With csrp3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001781 Zinc finger, LIM-type
Domain Details Per Protein
Protein Length Zinc finger, LIM-type
UniProtKB:F1QJC0 193
UniProtKB:Q5XJA9 193
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations