ZFIN ID: ZDB-GENE-041010-106
Gene Name: RNA polymerase II subunit I
Gene Symbol: polr2i    Nomenclature History

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Previous Name: zgc:103515 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have DNA-directed 5'-3' RNA polymerase activity; nucleic acid binding activity; and zinc ion binding activity. Predicted to be involved in maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; and transcription-coupled nucleotide-excision repair. Predicted to localize to RNA polymerase II, core complex. Orthologous to human POLR2I (RNA polymerase II subunit I).
Genome Resources: Alliance (1),  Gene:449992 (1),  Ensembl(GRCz11):ENSDARG00000040443 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:103515]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10431 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH polr2i HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH polr2i VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mRNA cleavage (more)
    Cellular Component nucleolus (more)
    Molecular Function DNA-directed 5'-3' RNA polymerase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA polr2i-201 (1)    Ensembl 744
    polr2i-202 (1)    Ensembl 333
    ncRNA polr2i-003 (1)    Ensembl 823
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM polr2i No data available
    MARKER RELATIONSHIPS
    polr2i Contained in: [BAC] CH211-202C21 (1), DKEY-113G17 (1) (order this)
    polr2i Encodes: [cDNA] MGC:103515 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001006013 (1) 774 nt
    Genomic GenBank:AL928979 193205 nt
    Select Tool
    Polypeptide UniProtKB:Q1LVK2 (1) 126 aa
    Sequence Information (all 14)
    ORTHOLOGY for polr2i ( Chr: 18 )
    CITATIONS (22)