Gene

svilc

ID
ZDB-GENE-041008-237
Name
supervillin c
Symbol
svilc Nomenclature History
Previous Names
  • im:7142403 (1)
  • si:dkeyp-57f11.2 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in actin filament severing; actin polymerization or depolymerization; and barbed-end actin filament capping. Predicted to localize to actin cytoskeleton and cytoplasm. Is expressed in anterior macula; hair cell; inner ear; posterior crista; and posterior macula. Orthologous to human SVIL (supervillin).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Pollock et al., 2016
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With svilc Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
myofibrillar myopathy 10 Alliance Myofibrillar myopathy 10 619040
Associated With svilc Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003128 Villin headpiece
Domain IPR007123 Gelsolin-like domain
Family IPR007122 Villin/Gelsolin
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Homologous_superfamily IPR036886 Villin headpiece domain superfamily
Domain Details Per Protein
Protein Length ADF-H/Gelsolin-like domain superfamily Gelsolin-like domain Villin/Gelsolin Villin headpiece Villin headpiece domain superfamily
UniProtKB:X1WDI1 1531
UniProtKB:X1WG70 188
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations