Gene
tsen15
- ID
- ZDB-GENE-041008-211
- Name
- TSEN15 tRNA splicing endonuclease subunit
- Symbol
- tsen15 Nomenclature History
- Previous Names
-
- im:7141062 (1)
- zgc:175162
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have nuclease activity and nucleic acid binding activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human TSEN15 (tRNA splicing endonuclease subunit 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7141062 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pontocerebellar hypoplasia type 2F | Alliance | Pontocerebellar hypoplasia, type 2F | 617026 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | tRNA endonuclease-like domain superfamily | tRNA intron endonuclease, catalytic domain-like superfamily | tRNA-splicing endonuclease subunit Sen15 |
|---|---|---|---|---|
|
UniProtKB:A5WV68
|
147 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
tsen15-201
(1)
|
Havana | 6943 nt |
Interactions and Pathways
No data available
Plasmids
No data available