Gene

usp4

ID
ZDB-GENE-041008-187
Name
ubiquitin specific peptidase 4 (proto-oncogene)
Symbol
usp4 Nomenclature History
Previous Names
  • im:7139722
  • unpEL (1)
  • wu:fa11d11
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have cysteine-type peptidase activity and thiol-dependent ubiquitin-specific protease activity. Involved in convergent extension; negative regulation of toll-like receptor signaling pathway; and protein deubiquitination. Predicted to localize to nucleus. Orthologous to human USP4 (ubiquitin specific peptidase 4).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp4 Human Ortholog
No data available
Associated With usp4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
Domain IPR028135 Ubiquitin-like domain, USP-type
Domain IPR028889 Ubiquitin specific protease domain
Domain IPR029346 Ubiquitin carboxyl-terminal hydrolase, C-terminal
Homologous_superfamily IPR035927 DUSP-like superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length DUSP-like superfamily Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase Peptidase C19, ubiquitin-specific peptidase, DUSP domain Ubiquitin carboxyl-terminal hydrolase, C-terminal Ubiquitin-like domain, USP-type Ubiquitin specific protease, conserved site Ubiquitin specific protease domain
UniProtKB:E7EZD6 1009
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations