ZFIN ID: ZDB-GENE-041008-127
Gene Name: Snf2-related CREBBP activator protein
Gene Symbol: srcap    Nomenclature History

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Previous Names: im:7137889, im:7138264

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have ATPase activity and histone binding activity. Predicted to be involved in gene silencing and histone exchange. Predicted to localize to Swr1 complex. Human ortholog(s) of this gene implicated in Floating-Harbor syndrome. Orthologous to human SRCAP (Snf2 related CREBBP activator protein).
Genome Resources: Alliance (1),  Gene:563456 (1),  Ensembl(GRCz11):ENSDARG00000005236 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7137889]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8992 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15343 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16953 Point Mutation Unknown Premature Stop ENU
    sa17300 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22109 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22110 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38898 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf2135 Unknown Exon 13 Unknown TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-srcap N/A 1
    DISEASE ASSOCIATED WITH srcap HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Floating-Harbor syndrome Alliance Floating-Harbor syndrome 136140
    DISEASE ASSOCIATED WITH srcap VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carboxylic acid metabolic process (more)
    Cellular Component Swr1 complex (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA srcap-201 (1)    Ensembl 14211
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM srcap No data available
    MARKER RELATIONSHIPS
    srcap Contained in: [BAC] DKEY-245I6 (1) (order this)
    srcap Encodes: [EST] IMAGE:7137889 (1), IMAGE:7138264 (1), wz12216
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NR_023320 (1)
    Genomic GenBank:AL929039 (1) 162385 nt
    Select Tool
    Polypeptide UniProtKB:E7FAZ7 (1) 3917 aa
    Sequence Information (all 18)
    ORTHOLOGY for srcap ( Chr: 12 )
    CITATIONS (17)