ZFIN ID: ZDB-GENE-041008-124
Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
Gene Symbol: grin2da    Nomenclature History

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Previous Names: NR2D.2 (1), im:7137805 (1), si:dkey-154b17.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have NMDA glutamate receptor activity and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential; glutamatergic synaptic transmission; and long-term synaptic potentiation. Predicted to localize to NMDA selective glutamate receptor complex and postsynaptic density membrane. Is expressed in presumptive neural retina; retina; and somite. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 46. Orthologous to human GRIN2D (glutamate ionotropic receptor NMDA type subunit 2D).
Genome Resources: Alliance (1),  Gene:449864 (1),  Ensembl(GRCz11):ENSDARG00000086207 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [IMAGE:7137805]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grin2da HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 46 Alliance Epileptic encephalopathy, early infantile, 46 617162
DISEASE ASSOCIATED WITH grin2da VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transport (more)
Cellular Component cell junction (more)
Molecular Function ion channel activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grin2da-201 (1)    Ensembl 6417
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grin2da No data available
MARKER RELATIONSHIPS
grin2da Contained in: [BAC] DKEY-154B17 (1) (order this)
grin2da Encodes: [EST] IMAGE:7137805 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_009294079 (1)
Genomic GenBank:BX950852 (1) 242320 nt Blast at MegaBLAST
Polypeptide UniProtKB:I3NI77 (1) 1916 aa
Sequence Information (all 11)
ORTHOLOGY for grin2da ( Chr: 19 )
CITATIONS (23)