ZFIN ID: ZDB-GENE-041008-108
Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 5
Gene Symbol: xrcc5
Sequence Ontology ID : SO:0000704

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Previous Names: im:7137560, Ku80 (1), si:ch211-239d11.4

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to contribute to double-stranded DNA binding activity; involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of apoptotic  ...
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7137560]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH xrcc5 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH xrcc5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (more)
Cellular Component Ku70:Ku80 complex (more)
Molecular Function ATP binding (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002035 (1)
  • InterPro:IPR005160 (1)
  • InterPro:IPR005161 (1)
  • InterPro:IPR006164 (1)
  • InterPro:IPR014893 (1)
  • InterPro:IPR016194 (1)
  • InterPro:IPR024193 (1)
  • InterPro:IPR036465 (1)
  • InterPro:IPR036494 (1)
  • PROSITE:PS50234 (1)
  • Pfam:PF02735 (1)
  • Pfam:PF03730 (1)
  • Pfam:PF03731 (1)
  • Pfam:PF08785 (1)
  • EC:3.6.4.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000062217 (1) 808
    ncRNA xrcc5-003 (1) 811
    mRNA xrcc5-201 (1) 2493
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM xrcc5 No data available
    MARKER RELATIONSHIPS
    xrcc5Contained in: [BAC] CH211-239D11 (1) (order this), CH211-241J8 (1) (order this)
    xrcc5Encodes: [EST] IMAGE:7137560 (1) (order this)
    [cDNA] MGC:136642 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017360 (1) 2540bp
    Genomic GenBank:CR339053 (1) 154689bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IB13 (1) 727aa
    Sequence Clusters UniGene:76405 (1)
    Sequence Information (all 18)
    OTHER xrcc5 GENE PAGES
  • Alliance (1)
  • Gene:449848 (1)
  • VEGA:OTTDARG00000026118 (1)
  • Ensembl(GRCz11):ENSDARG00000099298 (1)
  • ORTHOLOGY for xrcc5 (Chr: 9)
    CITATIONS (30)