ZFIN ID: ZDB-GENE-041008-1
Gene Name: RNA polymerase II subunit B
Gene Symbol: polr2b    Nomenclature History

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Previous Name: zgc:109952

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in transcription, DNA-templated. Predicted to localize to RNA polymerase II, core complex. Orthologous to human POLR2B (RNA polymerase II subunit B).
Genome Resources: Alliance (1),  Gene:100149268 (1),  Ensembl(GRCz11):ENSDARG00000098783 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:109952]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2635Tg Transgenic Insertion Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la019094Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12802 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH polr2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH polr2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transcription, DNA-templated (more)
    Cellular Component RNA polymerase II, core complex (more)
    Molecular Function DNA binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA polr2b-202 (1)    Ensembl 1345
    polr2b-203 (1)    Ensembl 1764
    ncRNA polr2b-003 (1)    Ensembl 360
    polr2b-004 (1)    Ensembl 823
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM polr2b No data available
    MARKER RELATIONSHIPS
    polr2b Contained in: [BAC] CH211-273E20
    polr2b Encodes: [cDNA] MGC:109952 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001024461 (1)
    Genomic GenBank:AL954718 (1) 163689 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IXL0 (1) 1174 aa
    Sequence Information (all 28)
    ORTHOLOGY for polr2b ( Chr: 14 )
    CITATIONS (30)