Gene

dse

ID
ZDB-GENE-041001-202
Name
dermatan sulfate epimerase
Symbol
dse Nomenclature History
Previous Names
  • si:dkey-121j17.2
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have chondroitin-glucuronate 5-epimerase activity. Predicted to be involved in chondroitin sulfate metabolic process and dermatan sulfate metabolic process. Predicted to localize to integral component of membrane. Is expressed in head; immature eye; pectoral fin; and somite. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 2. Orthologous to human DSE (dermatan sulfate epimerase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Habicher et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dse Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ehlers-Danlos syndrome, musculocontractural type 2 615539
Associated With dse Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR008929 Chondroitin AC/alginate lyase
Domain Details Per Protein
Protein Length Chondroitin AC/alginate lyase
UniProtKB:Q5RGL8 949
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA dse-201 (1) Havana 4405 nt
mRNA dse-202 (1) Ensembl 3047 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations