ZFIN ID: ZDB-GENE-041001-201
Gene Name: SET and MYND domain containing 2b
Gene Symbol: smyd2b    Nomenclature History

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Previous Names: si:dkey-121j17.3 (1), zgc:136609

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II complex binding activity and histone methyltransferase activity (H3-K36 specific). Involved in heart contraction and heart development. Predicted to localize to the cytosol and nucleus. Is expressed in muscle cell and somite. Orthologous to human SMYD2 (SET and MYND domain containing 2).
Genome Resources: Alliance (1),  Gene:568616 (1),  Ensembl(GRCz11):ENSDARG00000005629 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021770Tg Transgenic Insertion Unknown Unknown DNA
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-smyd2b N/A 2
MO2-smyd2b N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH smyd2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH smyd2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process heart contraction (more)
Cellular Component cytosol (more)
Molecular Function histone methyltransferase activity (H3-K36 specific) (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001214 SET domain
Domain IPR002893 Zinc finger, MYND-type
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA smyd2b-201 (1)    Ensembl 1553
smyd2b-203 (1)    Ensembl 760
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM smyd2b No data available
MARKER RELATIONSHIPS
smyd2b Contained in: [BAC] DKEY-121J17 (1) (order this)
smyd2b Encodes: [cDNA] MGC:136609 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001045291 (1) 2845 nt
Genomic GenBank:BX855610 (1) 139210 nt
Select Tool
Polypeptide UniProtKB:T1ECS2 (1) 437 aa
Sequence Information (all 20)
ORTHOLOGY for smyd2b ( Chr: 20 )
CITATIONS (27)