ZFIN ID: ZDB-GENE-041001-169
Gene Name: cholinergic receptor, muscarinic 5b
Gene Symbol: chrm5b    Nomenclature History

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Previous Names: chrm5, DrM5B (1), si:ch211-150c22.1, wu:fd11g11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway and chemical synaptic transmission. Predicted to localize to dendrite; integral component of plasma membrane; and synapse. Is expressed in eye. Orthologous to human CHRM5 (cholinergic receptor muscarinic 5).
Genome Resources: Alliance (1),  Gene:561491 (1),  Ensembl(GRCz11):ENSDARG00000069598 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Nuckels et al., 2011
Wild-type Stages, Structures: Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37058 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chrm5b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chrm5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component cell junction (more)
    Molecular Function G protein-coupled acetylcholine receptor activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chrm5b-201 (1)    Ensembl 1507
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chrm5b No data available
    MARKER RELATIONSHIPS
    chrm5b Contained in: [BAC] CH211-150C22 (1)
    chrm5b Encodes: [EST] fd11g11 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030160 (1) 1507 nt
    Genomic GenBank:BX784394 (1) 58454 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8RMF6 (1) 505 aa
    Sequence Information (all 10)
    ORTHOLOGY for chrm5b ( Chr: 20 )
    CITATIONS (22)