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General Information
ZIRC
ZFIN ID: ZDB-GENE-041001-133
Gene Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
Gene Symbol: mthfd1l
Sequence Ontology ID : SO:0001217

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Previous Names: fk48e08, si:dkey-25e12.5, si:dkey-25e12.6, wu:fk48e08

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have formate-tetrahydrofolate ligase activity; methenyltetrahydrofolate cyclohydrolase activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in  ...
GENE EXPRESSION
All Expression Data: Fig. 2 from Lee et al., 2012
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa915 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17397 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa23717 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44942 Point Mutation Unknown Unknown ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mthfd1l HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mthfd1l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA mthfd1l-003 (1) 541
    mthfd1l-004 (1) 766
    mRNA mthfd1l-201 (1) 5521
    mthfd1l-202 (1) 854
    mthfd1l-205 (1) 464
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mthfd1l No data available
    MARKER RELATIONSHIPS
    mthfd1l Contained in: [BAC] DKEY-25E12 (1) (order this)
    mthfd1l Encodes: [EST] fk48e08
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001242996 (1) 5750 bp
    Genomic GenBank:BX537272 (1) 210184 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8RW82 (1) 978 aa
    Sequence Clusters UniGene:79162 (1)
    Sequence Information (all 26)
    ORTHOLOGY for mthfd1l ( Chr: 20 )
    CITATIONS (19)