Gene

hint1

ID

ZDB-GENE-040927-8

Name

histidine triad nucleotide binding protein 1

Symbol

hint1 Nomenclature History

Previous Names

zgc:103764 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have catalytic activity. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Orthologous to human HINT1 (histidine triad nucleotide binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6892991 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hint1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Gamstorp-Wohlfart syndrome	Alliance	Neuromyotonia and axonal neuropathy, autosomal recessive	137200

Associated With hint1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019808	Histidine triad, conserved site
Domain	IPR011146	HIT-like domain
Family	IPR001310	Histidine triad (HIT) protein
Homologous_superfamily	IPR036265	HIT-like superfamily