ZFIN ID: ZDB-GENE-040917-2
Gene Name: ADAM metallopeptidase domain 10a
Gene Symbol: adam10a
Previous Names: adam10, wu:fc03d12
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa12400, sa17467, sa18021, sa18489, sa1909
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Reticulate acropigmentation of Kitamura 615537
{Alzheimer disease 18, susceptibility to} 615590
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Molecular Function metalloendopeptidase activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001590 (1)
  • InterPro:IPR001762 (1)
  • InterPro:IPR002870 (1)
  • InterPro:IPR024079 (1)
  • PROSITE:PS50214 (1)
  • PROSITE:PS50215 (1)
  • Pfam:PF00200 (1)
  • Pfam:PF01562 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA adam10a-001 (1) 4626
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adam10a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    adam10a Contained in: [BAC] CH211-162M14 (1) (order this), DKEY-261O24 (1)
    adam10a Encodes: [EST] fc03d12
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001159314 (1) 4450 bp
    Genomic GenBank:AL935053 (1) 138341 bp
    Select Tool
    Polypeptide UniProtKB:F1RA88 (1) 763 aa
    Sequence Clusters UniGene:105458 (1)
    Sequence Information (all 19)
    OTHER adam10a GENE PAGES
  • Gene:566044 (1)
  • VEGA:OTTDARG00000028580 (1)
  • Ensembl(Zv9):ENSDARG00000053468 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish adam10a 7  
    Human ADAM10 15 (15q22)
  • OMIM:602192
  • Gene:102
  • Mouse Adam10 9 ( 39.53 cM)
  • MGI:109548
  • Gene:11487
  • Orthology Details
    CITATIONS (14)