ZFIN ID: ZDB-GENE-040917-2
Gene Name: ADAM metallopeptidase domain 10a
Gene Symbol: adam10a
Previous Names: adam10, wu:fc03d12
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa1909 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12400 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa17467 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18021 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18489 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH adam10a HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Alzheimer's disease {Alzheimer disease 18, susceptibility to} 615590
    reticulate acropigmentation of Kitamura Reticulate acropigmentation of Kitamura 615537
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process Notch signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metalloendopeptidase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001590 (1)
  • InterPro:IPR001762 (1)
  • InterPro:IPR002870 (1)
  • InterPro:IPR024079 (1)
  • InterPro:IPR027053 (1)
  • PROSITE:PS50214 (1)
  • PROSITE:PS50215 (1)
  • Pfam:PF00200 (1)
  • Pfam:PF01562 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA adam10a-001 (1) 4626
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adam10a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    adam10aContained in: [BAC] CH211-162M14 (1) (order this), DKEY-261O24 (1) (order this)
    adam10aEncodes: [EST] fc03d12
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001159314 (1) 4450bp
    Genomic GenBank:AL935053 (1) 138341bp
    Select Tool
    Polypeptide UniProtKB:F1RA88 (1) 763aa
    Sequence Clusters UniGene:105458 (1)
    Sequence Information (all 20)
    OTHER adam10a GENE PAGES 
  • Gene:566044 (1)
  • VEGA:OTTDARG00000028580 (1)
  • Ensembl(GRCz10):ENSDARG00000053468 (1)
  • ORTHOLOGY for adam10a (Chr: 7) 
    Species Symbol Chromosome Accession # Evidence
    Human ADAM10 15
  • Gene:102
  • OMIM:602192
  • HGNC:188
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Mouse Adam10 9
  • MGI:109548
  • Gene:11487
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (15)