Gene

mast3a

ID

ZDB-GENE-040914-35

Name

microtubule associated serine/threonine kinase 3a

Symbol

mast3a Nomenclature History

Previous Names

mast3
im:6911368

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization; intracellular signal transduction; and protein phosphorylation. Orthologous to human MAST3 (microtubule associated serine/threonine kinase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6911368 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Shu et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mast3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 108	Alliance	Developmental and epileptic encephalopathy 108	620115

Associated With mast3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR001478	PDZ domain
Domain	IPR015022	Microtubule-associated serine/threonine-protein kinase, pre-PK domain
Domain	IPR037711	Microtubule-associated serine/threonine-protein kinase, catalytic domain
Domain	IPR041489	PDZ domain 6
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR023142	Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	AGC-kinase, C-terminal	Microtubule-associated serine/threonine-protein kinase, catalytic domain	Microtubule-associated serine/threonine-protein kinase, pre-PK domain	Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily	PDZ domain	PDZ domain 6	PDZ superfamily	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:F1QZB3 InterPro	1295
UniProtKB:A0A8M9PPY9 InterPro	1355
UniProtKB:A0A8M9PXC1 InterPro	1351
UniProtKB:A0A8M9Q0N6 InterPro	1354
UniProtKB:A0A8M9PSZ3 InterPro	1318

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations