ZFIN ID: ZDB-GENE-040914-13
Gene Name: heme oxygenase 2a
Gene Symbol: hmox2a    Nomenclature History

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Previous Names: im:6909100, si:dkey-44g23.7 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have heme binding activity and heme oxygenase (decyclizing) activity. Predicted to be involved in iron ion homeostasis; porphyrin-containing compound catabolic process; and response to oxidative stress. Predicted to localize to integral component of membrane. Is expressed in brain; gill; and liver. Orthologous to human HMOX2 (heme oxygenase 2).
Genome Resources: Alliance (1),  Gene:100002875 (1),  Ensembl(GRCz11):ENSDARG00000114695 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6909100]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8475 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13370 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hmox2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hmox2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heme oxidation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function heme oxygenase (decyclizing) activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hmox2a-202 (1)    Ensembl 826
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hmox2a No data available
    MARKER RELATIONSHIPS
    hmox2a Contained in: [BAC] DKEY-44G23 (1) (order this)
    hmox2a Encodes: [EST] IMAGE:6909100 (1)
    [cDNA] MGC:162585 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001103139 (1) 1582 nt
    Genomic GenBank:AL953841 (1) 219929 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A7MD59 (1) 310 aa
    Sequence Information (all 15)
    ORTHOLOGY for hmox2a ( Chr: 22 )
    CITATIONS (30)