ZFIN ID: ZDB-GENE-040912-89
Gene Name: CDC42 effector protein (Rho GTPase binding) 3
Gene Symbol: cdc42ep3    Nomenclature History

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Previous Name: zgc:92806 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have GTP-Rho binding activity. Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component biogenesis; and regulation of cell shape. Predicted to localize to cytoplasm; cytoskeleton; and plasma membrane. Is expressed in epidermis; muscle pioneer; pectoral fin musculature; peripheral olfactory organ; and tail bud. Orthologous to human CDC42EP3 (CDC42 effector protein 3).
Genome Resources: Alliance (1),  Gene:447829 (1),  Ensembl(GRCz11):ENSDARG00000052783 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [IMAGE:7158605]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ws2110Tg Transgenic Insertion Intron 2 Unknown DNA
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cdc42ep3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdc42ep3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of actin filament polymerization (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTP-Rho binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdc42ep3 No data available
    MARKER RELATIONSHIPS
    cdc42ep3 Encodes: [EST] IMAGE:7158605 (1)
    [cDNA] MGC:92806 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004568 (1)
    Genomic GenBank:CR774185 (1) 97539 nt
    Select Tool
    Polypeptide UniProtKB:Q66HU1 (1) 300 aa
    Sequence Information (all 12)
    ORTHOLOGY for cdc42ep3 ( Chr: 13 )
    CITATIONS (21)