Gene
msrb1b
- ID
- ZDB-GENE-040912-88
- Name
- methionine sulfoxide reductase B1b
- Symbol
- msrb1b Nomenclature History
- Previous Names
-
- sepx1b
- zgc:92822
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable single-stranded DNA 3'-5' DNA exonuclease activity and single-stranded DNA binding activity. Predicted to be involved in resolution of meiotic recombination intermediates. Predicted to act upstream of or within innate immune response. Predicted to be located in cytoplasm; cytoskeleton; and nucleus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency and spermatogenic failure 22. Orthologous to several human genes including MEIOB (meiosis specific with OB-fold).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92822 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002579 | Peptide methionine sulphoxide reductase MrsB domain |
| Family | IPR052150 | Methionine-R-sulfoxide reductase B1 |
| Family | IPR052469 | Meiosis-specific OB domain-containing |
| Homologous_superfamily | IPR011057 | Mss4-like superfamily |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
Domain Details Per Protein
| Protein | Additional Resources | Length | Meiosis-specific OB domain-containing | Methionine-R-sulfoxide reductase B1 | Mss4-like superfamily | Nucleic acid-binding, OB-fold | Peptide methionine sulphoxide reductase MrsB domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1NEL1 | InterPro | 110 | |||||
| UniProtKB:A0A2R8RIE0 | InterPro | 92 | |||||
| UniProtKB:F1R891 | InterPro | 466 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
msrb1b-201
(1)
|
Ensembl | 967 nt |
Interactions and Pathways
No data available
Plasmids
No data available