ZFIN ID: ZDB-GENE-040912-86
Gene Name: NADH:ubiquinone oxidoreductase subunit S6
Gene Symbol: ndufs6    Nomenclature History

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Previous Name: zgc:103774

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in cervical cancer and mitochondrial complex I deficiency. Orthologous to human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6).
Genome Resources: Alliance (1),  Gene:447913 (1),  Ensembl(GRCz11):ENSDARG00000056583 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:103774]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ndufs6 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mitochondrial complex I deficiency, nuclear type 9 618232
DISEASE ASSOCIATED WITH ndufs6 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process mitochondrial electron transport, NADH to ubiquinone (more)
Cellular Component membrane (more)
Molecular Function molecular_function (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ndufs6-201 (1)    Ensembl 508
ndufs6-202 (1)    Ensembl 622
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ndufs6 No data available
MARKER RELATIONSHIPS
ndufs6 Contained in: [BAC] DKEY-261I16 (1) (order this)
ndufs6 Encodes: [cDNA] MGC:103774 (1), MGC:192110 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001004651 (1) 513 nt
Genomic GenBank:BX571830 (1) 143486 nt
Select Tool
Polypeptide UniProtKB:Q1LWG2 (1) 129 aa
Sequence Information (all 15)
ORTHOLOGY for ndufs6 ( Chr: 19 )
CITATIONS (23)