ZFIN ID: ZDB-GENE-040912-82
Gene Name: vac14 homolog (S. cerevisiae)
Gene Symbol: vac14    Nomenclature History

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Previous Names: fb68e05, wu:fb68e05, zgc:100945

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to be involved in phosphatidylinositol biosynthetic process and positive regulation of kinase activity. Predicted to localize to PAS complex; endosome membrane; and extrinsic component of vacuolar membrane. Human ortholog(s) of this gene implicated in striatonigral degeneration. Orthologous to human VAC14 (VAC14 component of PIKFYVE complex).
Genome Resources: Alliance (1),  Gene:447912 (1),  Ensembl(GRCz11):ENSDARG00000014303 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7159610]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la014679Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa8773 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38043 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vac14 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vac14 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphatidylinositol biosynthetic process (more)
    Cellular Component endosome (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA vac14-201 (1)    Ensembl 3287
    ncRNA vac14-002 (1) 684
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM vac14 No data available
    MARKER RELATIONSHIPS
    vac14 Contained in: [BAC] DKEY-44K1 (1) (order this)
    vac14 Encodes: [EST] fb68e05, IMAGE:7159610 (1)
    [cDNA] MGC:100945 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004650 (1) 3225 nt
    Genomic GenBank:AL844894 (1) 220237 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4ITZ2 (1) 782 aa
    Sequence Information (all 15)
    ORTHOLOGY for vac14 ( Chr: 25 )
    CITATIONS (25)