ZFIN ID: ZDB-GENE-040912-78
Gene Name: transglutaminase 2, C polypeptide A
Gene Symbol: tgm2a    Nomenclature History

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Previous Names: TG2c (1), tgm2, zgc:101081

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Predicted to localize to mitochondrion. Is expressed in muscle; myotome; skeletal muscle; and somite. Orthologous to human TGM2 (transglutaminase 2).
Genome Resources: Alliance (1),  Gene:447909 (1),  Ensembl(GRCz11):ENSDARG00000070157 (1)
GENE EXPRESSION
All Expression Data: 11 figures from 4 publications
Directly Submitted Expression Data: 3 figures (2 images) from Thisse et al., 2004 [IMAGE:7137767]
  4 figures (3 images) from Thisse et al., 2004 [IMAGE:7146244]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37788 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tgm2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tgm2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peptide cross-linking (more)
    Cellular Component mitochondrion (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tgm2a-201 (1)    Ensembl 2120
    ncRNA ottdart00000062056 (1)    Ensembl 976
    ottdart00000062057 (1)    Ensembl 788
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tgm2a No data available
    MARKER RELATIONSHIPS
    tgm2a Contained in: [BAC] DKEY-65J6 (1) (order this), DKEY-151K14 (1) (order this)
    tgm2a Encodes: [EST] IMAGE:7137767 (1), IMAGE:7146244 (1)
    [cDNA] MGC:101081 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004647 (1) 2105 nt
    Genomic GenBank:CR545469 (1) 145419 nt
    Select Tool
    Polypeptide UniProtKB:F1R1A8 (1) 679 aa
    Sequence Information (all 12)
    ORTHOLOGY for tgm2a ( Chr: 23 )
    CITATIONS (22)