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ZIRC
ZFIN ID: ZDB-GENE-040912-64
Gene Name: rhotekin 2b
Gene Symbol: rtkn2b    Nomenclature History

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Previous Name: zgc:101635

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have GTP-Rho binding activity. Predicted to be involved in actomyosin contractile ring assembly; protein localization to mitotic actomyosin contractile ring; and septin ring organization. Predicted to localize to the actomyosin contractile ring. Is expressed in several structures, including head mesenchyme; lens; otic vesicle; pectoral fin bud; and solid lens vesicle. Orthologous to several human genes including RTKN (rhotekin).
Genome Resources: Alliance (1),  Gene:447899 (1),  Ensembl(GRCz11):ENSDARG00000052903 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43591 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rtkn2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rtkn2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Rho protein signal transduction (more)
    Cellular Component actomyosin contractile ring (more)
    Molecular Function GTP-Rho binding (more)
    GO Terms (all 10)
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rtkn2b No data available
    MARKER RELATIONSHIPS
    rtkn2b Encodes: [cDNA] MGC:101635 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004637 (1) 1332 bp
    Genomic GenBank:FO904924 (1) 93652 bp
    Select Tool
    Polypeptide UniProtKB:E7F528 (1) 499 aa
    Sequence Clusters UniGene:151355 (1)
    Sequence Information (all 16)
    ORTHOLOGY for rtkn2b ( Chr: 21 )
    CITATIONS (12)