Gene

cldn2

ID
ZDB-GENE-040912-26
Name
claudin 2
Symbol
cldn2 Nomenclature History
Previous Names
  • zgc:92260
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to localize to bicellular tight junction and plasma membrane. Is expressed in brain; eye; gonad; immune system; and liver. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 29. Orthologous to several human genes including CLDN2 (claudin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cldn2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Azoospermia, obstructive, with nephrolithiasis 301060
Associated With cldn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017974 Claudin, conserved site
Family IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Family IPR005411 Claudin-2
Family IPR006187 Claudin
Domain Details Per Protein
Protein Length Claudin Claudin-2 Claudin, conserved site PMP-22/EMP/MP20/Claudin superfamily
UniProtKB:Q66HX3 253
UniProtKB:F1QKA9 270
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations