ZFIN ID: ZDB-GENE-040912-26
Gene Name: claudin 2
Gene Symbol: cldn2
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:92260

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have structural molecule activity; predicted to localize to the bicellular tight junction, integral component of membrane, and plasma membrane; orthologous to several human genes  ...
GENE EXPRESSION
All Expression Data: 6 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92260]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43695 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cldn2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cldn2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biological_process (more)
    Cellular Component bicellular tight junction (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004031 (1)
  • InterPro:IPR005411 (1)
  • InterPro:IPR006187 (1)
  • InterPro:IPR017974 (1)
  • PROSITE:PS01346 (1)
  • Pfam:PF00822 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cldn2-001 (1) 1873
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cldn2 No data available
    MARKER RELATIONSHIPS
    cldn2Contained in: [BAC] DKEY-38K9 (1) (order this)
    cldn2Encodes: [cDNA] MGC:92260 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001004559 (1) 1821bp
    Genomic GenBank:BX530030 (1) 180154bp
    Select Tool
    Polypeptide UniProtKB:F1QKA9 (1) 270aa
    Sequence Clusters UniGene:89868 (1)
    Sequence Information (all 12)
    OTHER cldn2 GENE PAGES
  • Alliance (1)
  • Gene:562525 (1)
  • VEGA:OTTDARG00000022606 (1)
  • Ensembl(GRCz11):ENSDARG00000044387 (2)
  • ORTHOLOGY for cldn2 (Chr: 21)
    CITATIONS (25)