Gene

ass1

ID
ZDB-GENE-040912-178
Name
argininosuccinate synthase 1
Symbol
ass1 Nomenclature History
Previous Names
  • ass (1)
  • wu:fb95a04
  • wu:fc01e08
  • zgc:92051
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable argininosuccinate synthase activity. Predicted to be involved in arginine biosynthetic process; argininosuccinate metabolic process; and urea cycle. Predicted to act upstream of or within amino acid biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including DEL; ball; brain; endoderm; and forerunner cell group. Human ortholog(s) of this gene implicated in citrullinemia; classic citrullinemia; hepatocellular carcinoma; and melanoma. Orthologous to human ASS1 (argininosuccinate synthase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ass1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
classic citrullinemia Alliance Citrullinemia 215700
Associated With ass1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018223 Argininosuccinate synthase, conserved site
Family IPR001518 Argininosuccinate synthase
Family IPR023434 Argininosuccinate synthase, type 1 subfamily
Homologous_superfamily IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body
Domain Details Per Protein
Protein Length Argininosuccinate synthase Argininosuccinate synthase, conserved site Argininosuccinate synthase, type 1 subfamily Argininosuccinate synthetase, catalytic/multimerisation domain body Rossmann-like alpha/beta/alpha sandwich fold
UniProtKB:Q66I24 414
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations