ZFIN ID: ZDB-GENE-040912-175
Gene Name: nuclear casein kinase and cyclin-dependent kinase substrate 1a
Gene Symbol: nucks1a    Nomenclature History

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Previous Names: nucks1, wu:fb16a10, wu:fb16h08, wu:fb36b01, wu:fb82a01, wu:fe37f10, wu:gcd26e12, zgc:86878

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have double-stranded DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination and interstrand cross-link repair. Predicted to localize to cytoplasm and nuclear chromatin. Is expressed in brain; pectoral fin; and pharyngeal arch 3-7 skeleton. Orthologous to human NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1).
Genome Resources: Alliance (1),  Gene:447862 (1),  Ensembl(GRCz11):ENSDARG00000078473 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012032Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41902 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45440 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nucks1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nucks1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function kinase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nucks1a-201 (1)    Ensembl 3802
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nucks1a No data available
    MARKER RELATIONSHIPS
    nucks1a Contained in: [BAC] CH211-117K10 (1)
    nucks1a Encodes: [EST] eu439 (1), fb16a10, fb16h08 (order this), fb36b01, fb82a01 (1) (order this), fe37f10, gcd26e12 (1) (order this)
    [cDNA] MGC:86878 (1), MGC:173795 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004601 (1) 3194 nt
    Genomic GenBank:AL929286 (1) 168222 nt
    Select Tool
    Polypeptide UniProtKB:Q66I37 (1) 305 aa
    Sequence Information (all 33)
    ORTHOLOGY for nucks1a ( Chr: 11 )
    CITATIONS (26)