ZFIN ID: ZDB-GENE-040912-16
Gene Name: pyridoxal-dependent decarboxylase domain containing 1
Gene Symbol: pdxdc1    Nomenclature History

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Previous Names: wu:fj29c10, zgc:92179 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have sphinganine-1-phosphate aldolase activity. Predicted to be involved in ameboidal-type cell migration and sphingolipid catabolic process. Predicted to localize to endoplasmic reticulum. Is expressed in EVL; notochord; periderm; pharynx; and polster. Orthologous to human PDXDC1 (pyridoxal dependent decarboxylase domain containing 1).
Genome Resources: Alliance (1),  Gene:447813 (1),  Ensembl(GRCz11):ENSDARG00000101886 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2004 [IMAGE:7160098]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33245 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40115 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdxdc1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdxdc1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carboxylic acid metabolic process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdxdc1-201 (1)    Ensembl 3864
    ncRNA pdxdc1-002 (1)    Ensembl 495
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdxdc1 No data available
    MARKER RELATIONSHIPS
    pdxdc1 Contained in: [BAC] DKEYP-72E1 (1)
    pdxdc1 Encodes: [EST] fj29c10, IMAGE:7160098 (1)
    [cDNA] MGC:92179 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001004552 (1) 3684 nt
    Genomic GenBank:CR388147 (1) 194517 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QBE4 (1) 782 aa
    Sequence Information (all 26)
    ORTHOLOGY for pdxdc1 ( Chr: 3 )
    CITATIONS (19)