Gene

pfkma

ID
ZDB-GENE-040912-135
Name
phosphofructokinase, muscle a
Symbol
pfkma Nomenclature History
Previous Names
  • pfkm (1)
  • wu:fc58g11
  • zgc:92344
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have several functions, including 6-phosphofructokinase activity; adenyl ribonucleotide binding activity; and fructose-6-phosphate binding activity. Predicted to be involved in several processes, including canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and protein homotetramerization. Predicted to localize to 6-phosphofructokinase complex and membrane. Is expressed in male organism; musculature system; myotome; and pectoral fin musculature. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKM (phosphofructokinase, muscle).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pfkma Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
glycogen storage disease VII Alliance Glycogen storage disease VII 232800
Associated With pfkma Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015912 Phosphofructokinase, conserved site
Domain IPR000023 Phosphofructokinase domain
Family IPR009161 ATP-dependent 6-phosphofructokinase, eukaryotic-type
Family IPR022953 ATP-dependent 6-phosphofructokinase
Family IPR041914 ATP-dependent 6-phosphofructokinase, vertebrate-type
Homologous_superfamily IPR035966 Phosphofructokinase superfamily
Domain Details Per Protein
Protein Length ATP-dependent 6-phosphofructokinase ATP-dependent 6-phosphofructokinase, eukaryotic-type ATP-dependent 6-phosphofructokinase, vertebrate-type Phosphofructokinase, conserved site Phosphofructokinase domain Phosphofructokinase superfamily
UniProtKB:Q66HV8 784
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations