ZFIN ID: ZDB-GENE-040912-135
Gene Name: phosphofructokinase, muscle a
Gene Symbol: pfkma    Nomenclature History

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Previous Names: pfkm (1), wu:fc58g11, zgc:92344

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have several functions, including 6-phosphofructokinase activity; adenyl ribonucleotide binding activity; and fructose-6-phosphate binding activity. Predicted to be involved in several processes, including canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and protein homotetramerization. Predicted to localize to 6-phosphofructokinase complex and membrane. Is expressed in male organism; musculature system; myotome; and pectoral fin musculature. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKM (phosphofructokinase, muscle).
Genome Resources: Alliance (1),  Gene:447836 (1),  Ensembl(GRCz11):ENSDARG00000014179 (1)
GENE EXPRESSION
All Expression Data: 14 figures from 4 publications
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [IMAGE:7151834]
  7 figures (8 images) from Thisse et al., 2004 [IMAGE:7147892]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pfkma HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
glycogen storage disease VII Alliance Glycogen storage disease VII 232800
DISEASE ASSOCIATED WITH pfkma VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process fructose 6-phosphate metabolic process (more)
Cellular Component cytoplasm (more)
Molecular Function 6-phosphofructokinase activity (more)
GO Terms (all 22)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pfkma-201 (1)    Ensembl 2601
ncRNA pfkma-002 (1)    Ensembl 945
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pfkma No data available
MARKER RELATIONSHIPS
pfkma Contained in: [BAC] CH211-156J22 (1)
pfkma Encodes: [EST] IMAGE:7147892 (1), IMAGE:7151834 (1)
[cDNA] MGC:92344 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001004575 (1) 2627 nt
Genomic GenBank:CR354381 (1) 104229 nt
Select Tool
Polypeptide UniProtKB:Q66HV8 (1) 784 aa
Sequence Information (all 10)
ORTHOLOGY for pfkma ( Chr: 23 )
CITATIONS (36)